PPI's and Mood

[esimpkins]

To all

Anyone who has taken PPI's for a long time, Have you noticed your irritability increases. I have been taking a double dose of Prevacid (30Mg each dose) for about six weeks and found I am impatient, irritable and sometimes downright rude. I am sure part of it is becuase I am not feeling great but it sure seems strange.Can find nothing in the paperwork about this side effect

Thoughts

Erik

[Aerta]

If you look at many of the medication and fundo threads, you will see that there are a few of us who found the same thing. The difference between my being on PPI's and off has been dramatic according to everyone I know. And I find I laugh a lot more and worry a lot less :-)

Aerta

[linbee]

Yup, I've posted a few times recently on this. I only took PPI's for a few months, and only a once-a-day dose, and I still was very " impatient, irritable and sometimes downright rude." I saw (as did my husband, who had somehow put up with me) a huge difference when I came off the PPI.

I do remember seeing something in the side effects list somewhere about "depression, " which was the closest they came to mood changes.

I'm lucky that I seem to do okay on an H2 blocker and various natural remedies and so far can manage without the PPI.

linbee

[LSAT]

If you read the package insert under adverse reactions, the following are listed.....agitation, anxiety, depersonalization, depression (among others).