Tricia-I would like reiterate the main two points I made earlier today in a hew thread. In response to your question on what mechanism would cause reflux symptoms in low acid individuals, as you stated damage could occur in reflux with a PH of 4 so I fail to understand the mystery. Second you did not respond to the question of how you ascertained that doctors who prescribe PPI's do not believe that overly acidic stomachs is the problem. Nor did you respond to the point of what degree do they actually have meaningful tests which screen for too little or too much acid. I do not ask these questions again in any sense of badgering, but only to make sure that you understand I feel the questions were not answered and that I see them as important. A final question is what are your thoughts on those who take Betaine and other acidic supplements which improve their symptoms. Do you believe such individuals are actually suffering from hypochlorhydria or something else?